师资队伍

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制药工程系教师

陈健强



陈健强,博士;硕士生导师。近年来主要从事光催化的烷氧酰基自由基以及磺酰基自由基的反应研究,以第一作者或通信作者身份在Nat, Commun., Green Chem., Org. Lett., Org. Chem. Front.,等国际权威期刊发表论文近20篇,授权多项发明专利。邮箱:chenjq@tzc.edu.cn

学习与工作经历:

2008.09-2012.06 南通大学 化学化工学院 学士

2013.09-2018.06 兰州大学 化学化工学院 博士

2018.07-2019.03 南京大学 化学化工学院 博士后

2019.11-至今 台州学院 医药化工学院 讲师

研究方向:

可见光催化;烷氧酰基自由基;药物分子合成

主持及参与的项目:

国家自然科学基金,重点项目,《催化串联反应高效构筑天然产物与药物分子骨架》,(21632003)2017.1-2022.1, 300 万,参与

国家自然科学基金,青年项目,《基于可见光促进的不对称烷氧酰基化合成手性酯类化合物》,(22201201)2023.1-2025.1230万,主持

浙江省自然科学基金,探索项目,《光催化烷氧酰基化合成氨基酸》,(LY23B020001)2023.1-2025.1210万,主持

代表性论文:

1. J.-Q. Chen,* X. Tu, Q. Tang, K. Li, L. Xu, S. Wang, M. Ji, Z. Li,* J. Wu* Efficient Access to Aliphatic Esters by Photocatalyzed Alkoxycarbonylation of Alkenes with Alkyloxalyl Chlorides, Nat. Commun., 2021, 12, 5328. (SCI一区) (Nature 子刊)


2. J.-Q. Chen, N. Liu, Q. Hu, J. Liu, J. Wu, Q. Cai, J. Wu,* Photocatalytic Three-Component Radical Cascade: A General Route to Heterocyclic-Substituted Alkyl Sulfones. Org. Chem. Front., 2021, 8, 5316. (SCI一区)


3. M. Ji, L. Xu, X. Luo, M. Jiang, S. Wang, J.-Q. Chen,* J. Wu,* Alkoxycarbonyl Radicals from Alkyloxalyl Chlorides: Photoinduced Synthesis of Isoquinolinediones under Visible Light Rrradiation, Org. Chem. Front., 2021, 8, 6704. (SCI一区)

4. J.-Q. Chen, X. Tu, B. Qin, S. Huang, J. Zhang,* J. Wu,* Synthesis of Ester-Substituted Indolo[2,1‑a]isoquinolines via Photocatalyzed Alkoxycarbonylation/ Cyclization Reactions, Org. Lett., 2022, 24, 642. (SCI一区)(高被引论文)

5. J. Huang, F. Liu, X. Wu, J.-Q. Chen,* J. Wu,* Recent Advances in the Reactions of Silacyclobutanes and Their Applications, Org. Chem. Front., 2022, 9, 2840. (SCI一区)

6. X. Wang, Y. Chen, P. Liang, J.-Q. Chen,* J. Wu,* Synthesis of β-Fluorocarboxylic Esters via Organophotoredox-Catalyzed Fluoroalkoxycarbonylation of Alkenes in EtOH, Green Chem., 2022, 24, 5077. (SCI一区)

7. X. Wang, Y. Chen, P. Liang, J.-Q. Chen,* J. Wu, * Synthesis of γ-Amino Acids via Photocatalyzed Intermolecular Carboimination of Alkenes, Org. Chem. Front., 2022, 9, 4328. (SCI一区)

8. J.-Q. Chen,* X. Luo, M. Chen, Y. Chen, J. Wu,* Visible-Light-Induced 1,7-Enynes Dicyclization: Synthesis of Ester-Substituted Benzo[j]phenanthridines. Org. Lett., 2023, 25, 1978. (SCI一区)

9. J.-Q. Chen, Q. Chen, B. Chen,* J. Wu,* Visible-Light-Induced Alkoxycarbonylation /Cyclization of 1,7-Enynes: Synthesis of Dihydropyranones containing All-Carbon Quaternary Centers. Org. Chem. Front., 2023, 10, 2018. (SCI一区)

10. J.-Q. Chen, Q. Li, W. Xie, J. Wu,* Enantioselective Synthesis of Chiral Sulfones by Hydrogen-Bonding/Organophotoredox Co-catalyzed Asymmetric Sulfonylation. Org. Chem. Front., 2023, 10, 2251. (SCI一区)

11. M. Chen, W. Sun, J. Yang, L. Yuan, J.-Q. Chen,* J. Wu,* Metal-Free Photosensitized Aminosulfonylation of Alkenes: A Practical Approach to β-Amido Sulfones. Green Chem., 2023, 25, DOI: 10.1039/D3GC01059G. (SCI一区)